Improvement of exertional dyspnea and breathing pattern of inspiration to expiration after bronchial thermoplasty

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A case of pulmonary cyst and pneumothorax after bronchial thermoplasty

Bronchial thermoplasty (BT) is a bronchoscopic treatment for severe asthma using thermal energy to reduce smooth muscle in the bronchial wall. A 47-year-old man underwent BT for uncontrolled severe asthma despite maximal pharmacological treatment. After a third procedure, he experienced hypoxaemia because of complete bilateral upper lobe atelectasis. A pulmonary cyst suddenly emerged in to the ...

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Bronchial thermoplasty.

Asthma severity was defi ned according to recognized standards at the time the Asthma Intervention Research (AIR)-2 trial was designed. Th us, in response to the authors’ question, 86% of the BT group and 88% of the sham group were indeed severe per American Th oracic Society criteria for severe refractory asthma 3 and had, on average, only 17% symptom-free days, further demonstrating poor asth...

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Nerve ablation after bronchial thermoplasty and sustained improvement in severe asthma

BACKGROUND Bronchial thermoplasty (BT) is a non-pharmacological intervention for severe asthma whose mechanism of action is not completely explained by a reduction of airway smooth muscle (ASM). In this study we analyzed the effect of BT on nerve fibers and inflammatory components in the bronchial mucosa at 1 year. METHODS Endobronchial biopsies were obtained from 12 subjects (mean age 47 ± 1...

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Bronchial thermoplasty: Quo vadis?

I ntroduction: In recent years a number of emerging new therapies have become available for the treatment of severe asthma among which bronchial ther-moplasty is the only nonpharmacologic intervention that has been approved by the United States Food and Drug Administration in 2010. 1 Although bronchial thermoplasty has great promise for the patient with severe asthma and is now within the thera...

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Bronchial thermoplasty in asthma.

In this review we discuss the potential of a new procedure, termed Bronchial Thermoplasty to prevent serious consequences resulting from excessive airway narrowing. The most important factor in minimizing an asthmatic attack is limiting the degree of smooth muscle shortening. The premise that airway smooth muscle can be either inactivated or obliterated without any long-term alteration of other...

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ژورنال

عنوان ژورنال: Allergy, Asthma & Clinical Immunology

سال: 2018

ISSN: 1710-1492

DOI: 10.1186/s13223-018-0276-3